Tenofovir CAS 147127-20-6 Assay 98.0%~102.0% API Anti-HIV Factory

Short Description:

Name: Tenofovir

CAS: 147127-20-6

Appearance: White or Off-White Crystalline Powder

Assay: 98.0%~102.0% (on anhydrous basis)

Tenofovir is used for the treatment of Chronic Heptatitis B as well as prevention and treatment of HIV/AIDS.

High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Commercial Supply Tenofovir Related Intermediates:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl Isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
Adenine CAS 73-24-5

Chemical Properties:

Name	Tenofovir
Synonyms	(R)-PMPA; (R)-9-(2-Phosphonomethoxypropyl)Adenine
CAS Number	147127-20-6
CAT Number	RF-API07
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C9H14N5O4P
Molecular Weight	287.22
Melting Point	276.0-280.0℃
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White or Almost White Crystalline Powder
Assay / Analysis Method	98.0%~102.0% (on anhydrous basis)
Solubility	Slightly Soluble in Water (0.1g in 100ml); Practically Insoluble in Methanol(0.01g in 100ml and over)
Identification UV	Absorbance at about 261nm
Identification HPLC	The retention time of the principal peak in the test sample should match with that of the standard
Sulphate Ash	≤1.5%
Water (K.F)	≤3.0%
Specific Optical Rotation	-19.0° ~ -23.0° (at 25℃ anhydrous basis)
PMPA Monoester Impurity	≤1.5% (HPLC)
Any Single Max Impurity	≤0.5% (HPLC)
Total Impurities	≤3.0% (HPLC)
Enantiomeric Purity	≤0.5% (HPLC)
9-Propenyl Adenine	≤75ppm (HPLC)
Test Standard	Enterprise Standard

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.

Advantages:

FAQ:

Application:

Tenofovir (CAS: 147127-20-6) is an acyclic phosphonate nucleotide analogue and reverse-transcriptase inhibitor (NtRTI). It is used as an anti-HIV agent. Antiviral. Tenofovir disoproxil (Viread) is the first nucleotide analogue approved by the American FDA to treat HIV-1 infections. Tenofovir is a drug used for the treatment of chronic heptatitis B as well as prevention and treatment of HIV/AIDS. It inhibits the activity of HIV reverse transcriptase through competing with the natural substrate deoxyadenosine 5’-triphosphate, causing the termination of DNA chain.