Benfotiamine CAS 22457-89-2 Assay 98.0%~102.0%

Short Description:

Chemical Name: Benfotiamine

Synonyms: S-Benzoylthiamine O-Monophosphate

CAS: 22457-89-2

Assay: 98.0%~102.0%

White Crystal or White Crystalline Powder

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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22457-89-2 - Description:

Ruifu Chemical is the leading manufacturer of Benfotiamine (S-Benzoylthiamine O-Monophosphate) (CAS: 22457-89-2) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Benfotiamine, Please contact: alvin@ruifuchem.com

22457-89-2 - Chemical Properties:

Chemical Name Benfotiamine 
Synonyms S-Benzoylthiamine O-Monophosphate
Stock Status In Stock, Commercial Production  
CAS Number 22457-89-2
Molecular Formula C19H23N4O6PS 
Molecular Weight 466.45 g/mol
Melting Point 165℃ 
Density 1.444±0.06 g/cm3
Sensitive Heat Sensitive 
COA & MSDS Available
Origin Shanghai, China
Brand Ruifu Chemical

22457-89-2 - Specifications:

Items Specifications  Results
Appearance White Crystal or White Crystalline Powder Complies
Identification A IR Spectra is Accordant with that of Benfotiamine RS  Complies
Identification B The Retention Time of Main Peak is Accordant with that of Benfotiamine RS Complies
Clarity & Color of Solution             Clear and Colorless Complies
Loss on Drying  ≤1.50% 0.62%
Chloride  ≤0.053% <0.053%
Sulphate ≤0.011% <0.011%
Heavy Metals  ≤20ppm  <20ppm
Related Substances    
TMP ≤0.15% <0.025%
Benzoic Acid ≤0.10%  N/D 
Thiamine ≤0.10% 0.06% 
Amide  ≤0.40%  0.08% 
Single Unknown Impurity  ≤0.10%  N/D  
Total Impurities ≤1.50% 0.33%
Residual Solvents
Dichloromethane ≤600ppm N/D  
Isopropanol ≤300ppm 64ppm
Microbial Limits
Total Bacteria ≤100cfu/g <10cfu/g
Yeast and Mould ≤50cfu/g <10cfu/g
Escherichia Coli Not Detectable N/D  
Assay 98.0%~102.0% (Dry Basis) 99.6% 
Infrared Spectrum  Conforms to Structure   Complies  
NMR Spectrum  Conforms to Structure  Complies
Conclusion  The product has been tested and complies with the given specifications  

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

22457-89-2 - Safety Information:

Hazard Symbols Xn - Harmful
Risk Codes
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany 2
RTECS DH6910000

22457-89-2 - Biological Activity:

Benfotiamine (S-Benzoylthiamine O-Monophosphate) (CAS: 22457-89-2), Vitamin B1 analog. Synthetic S-acyl derivative of Thiamine. Benfotiamine is a fat-soluble analog of vitamin B1, which has higher absorption rate and bioavailability than vitamin B1. It is often used as a food supplement for diabetic complications. Benfotiamine has direct antioxidant capacity and can prevent DNA damage. 

22457-89-2 - Function:

Function of Benfotiamine (CAS: 22457-89-2)
1. Benfotiamine powder is used for the prevention and treatment of vitamin B1 deficiency;
2. For vitamin B1 demand increase, with inadequate intake from foods supplies (fatigue, hyperthyroidism, pregnancy, lactation, during strenuous manual labor, etc.);
3. Benfotiamine is used in the treatment of nonalcoholic wernicke encephalopathy;
4. To treat beriberi;
5. Used in the following diseases, speculation, and vitamin B1 deficiency and metabolic disorders associated with treatment, such as: Neuralgia; Muscle pain, joint pain; Peripheral neuritis, peripheral nerve palsy; Myocardial metabolic disorders; Constipation and other gastrointestinal motor function obstacle.

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