Baricitinib Intermediate CAS 941685-27-4 Purity >98.0% (HPLC)

Short Description:

Chemical Name: 4-(1H-Pyrazol-4-yl)-7-[[2-(Trimethylsilyl)ethoxy]methyl]-7H-Pyrrolo[2,3-d]pyrimidine

CAS: 941685-27-4

Purity: >98.0% (HPLC)

Appearance: White Powder

Intermediate of Baricitinib (CAS: 1187594-09-7)

Contact: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

941685-27-4 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 4-(1H-Pyrazol-4-yl)-7-[[2-(Trimethylsilyl)ethoxy] methyl]-7H-Pyrrolo[2,3-d]pyrimidine (CAS: 941685-27-4) with high and stable quality control, an intermediate of Baricitinib (CAS: 1187594-09-7), used for the treatment of rheumatoid arthritis.
Ruifu Chemical has been supplying pharmaceutical intermediates and APIs more than 15 years. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available.
Purchase Baricitinib intermediates, Please contact us by e-mail: alvin@ruifuchem.com for quotation requests. Please provide quantity, purity, and any other specific requirements.

Intermediates of Baricitinib (CAS: 1187594-09-7):

Baricitinib API	CAS 1187594-09-7
1-Boc-3-Azetidinone	CAS 398489-26-4
3-Hydroxyazetidine Hydrochloride	CAS 18621-18-6
1-Boc-3-(Cyanomethylene)azetidine	CAS 1153949-11-1
2-[1-(Ethylsulfonyl)azetidin-3-ylidene]acetonitrile	CAS 1187595-85-2
2-(Azetidin-3-ylidene)acetonitrile Hydrochloride	CAS 1314910-43-4
1-(1-Ethoxyethyl)-1H-Pyrazole-4-Boronic Acid Pinacol Ester	CAS 1029716-44-6
4-(1H-Pyrazol-4-yl)-7-[[2-(Trimethylsilyl)ethoxy]methyl]-7H-Pyrrolo[2,3-d]pyrimidine	CAS 941685-27-4

941685-27-4 - Chemical Properties:

Chemical Name	4-(1H-Pyrazol-4-yl)-7-[[2-(Trimethylsilyl)ethoxy]methyl]-7H-Pyrrolo[2,3-d] pyrimidine
Synonyms	4-(4-Pyrazolyl)-7-[[2-(Trimethylsilyl)ethoxy]methyl]-7H-Pyrrolo[2,3-d]pyrimidine; Trimethyl-[2-[[4-(1H-Pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methoxy]ethyl]silane
Stock Status	In Stock, Commercial Production
CAS Number	941685-27-4
Molecular Formula	C15H21N5OSi
Molecular Weight	315.45 g/mol
Density	1.20±0.10 g/cm3
Store Under Inert Gas	Store Under Inert Gas (Nitrogen or Argon) at 2~8℃
COA & MSDS	Available
Origin of Product	Shanghai, China
Product Categories	Pharmaceutical Intermediates
Brand	Ruifu Chemical

941685-27-4 - Specifications:

Items	Specifications	Results
Appearance	White Powder	White Powder
Melting Point	180.0~190.0℃	183.4~184.5℃
Water by Karl Fischer	<0.50%	0.09%
Purity / Analysis Method	>98.0% (HPLC)	99.1%
1H NMR Spectrum	Conforms to Structure	Conforms
Mass Spectrum	Conforms to Structure	Conforms
Conclusion	The product has been tested and complies with the given specifications
Usage	Intermediate of Baricitinib (CAS: 1187594-09-7), Rheumatoid Arthritis

941685-27-4 - Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃), well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

941685-27-4 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

941685-27-4 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

941685-27-4 - Risk and Safety:

Hazard Symbols Xn - Harmful
Risk Codes 22 - Harmful if swallowed
Hazard Class IRRITANT

941685-27-4 - Application:

4-(1H-Pyrazol-4-yl)-7-[[2-(Trimethylsilyl)ethoxy]methyl]-7H-Pyrrolo[2,3-d]pyrimidine (CAS: 941685-27-4), an intermediate of Baricitinib (CAS: 1187594-09-7). For the treatment of moderately to severely active rheumatoid arthritis (RA) in adults, patients who are intolerant of one or more anti-rheumatic drugs can be treated with this product. This product can be used as a single drug or in combination with methotrexate. combination therapy.
If you are interested in our products or have any questions, please feel free to contact us! Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.